婴儿银安全性;一个系统的范围审查
Patrick K O'Donohoe1,2, Ryan Leon1, David J A Orr1,2,3,4
1Department of Plastic Surgery, Children's Health Ireland at Crumlin, Dublin 12, Ireland.
概括
基于银的带对于婴儿来说是安全的,只要在高风险的伤口上明智地使用. 这次审查没有发现严重的不良事件,尽管在某些情况下注意到血清银水平升高.
科学领域:
- 儿科伤口护理 儿科伤口护理
- 皮肤病学 皮肤病学
- 毒理学 毒理学 毒理学
背景情况:
- 基于银的包裹对于复杂的伤口是常见的.
- 有关婴儿系统性银毒性存在担忧.
- 在1岁以下的儿童中使用需要仔细考虑.
研究的目的:
- 系统地审查有关1岁以下婴儿银基带的文献.
- 为了识别并发症,不良事件和血清银水平.
- 为了为这个患者群体提供临床决策信息.
主要方法:
- 按照乔安娜·布里格斯研究所的方法进行系统范围审查.
- 在医学数据库和灰色文献中进行搜索.
- 纳入标准:1岁以下儿童的银基带;结果:并发症,不良事件,血清银含量.
主要成果:
- 从599个已识别的来源中审查了110个来源.
- 伤口感染是最常见的并发症 (31个来源).
- 报告没有阿尔吉里亚,克尔尼克特勒斯或甲基红蛋白血症;6个来源指出血清银的升高没有不良事件.
结论:
- 为高危婴儿伤口预留银.
- 考虑到系统吸收风险的伤口面积和治疗时间.
- 建议对未来的证据进行标准化数据收集.
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