关于自身造血细胞移植和免疫效应细胞治疗的门诊计划的政策和观点
Scott R Goldsmith1, May San-Rozano1, Justine Katindoy1
1Department of Hematology and Hematopoietic Cell Transplantation, City of Hope Comprehensive Cancer Center, Duarte, CA, United States.
Frontiers in immunology
|August 21, 2024
概括
门诊自主造血细胞移植 (AutoHCT) 和免疫效应细胞 (IEC) 疗法可节省成本,改善患者的生活质量. 开发成功的门诊计划需要专门的协议,训练有素的员工和强大的支持性护理.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 卫生政策 卫生政策
背景情况:
- 自主造血细胞移植 (AutoHCT) 已经过渡到门诊,改善了患者的治疗结果并降低了成本.
- 免疫效应细胞 (IEC) 疗法正在成为各种恶性瘤的重要治疗方法.
- 目前的金融模式可能不支持IEC治疗的住院治疗,需要门诊计划的开发.
研究的目的:
- 审查门诊AutoHCT和IEC计划的指导方针和学术经验.
- 描述机构在管理这些门诊治疗中的角色和责任.
- 为更广泛地实施门诊AutoHCT和IEC计划提供可行的建议.
主要方法:
- 政策和实践审查.政策和实践审查.
- 分析已发表的学术经验.
- 描述机构的角色和责任.
主要成果:
- 门诊AutoHCT已经证明成功,为IEC疗法提供了一个模板.
- 成功的门诊计划需要专门的协议,训练有素的人员和全面的支持系统.
- 护理人员的教育和审查对于患者的安全和计划的成功至关重要.
结论:
- 将IEC疗法转移到门诊环境对于财务可行性和患者生活质量至关重要.
- 综合的门诊计划需要标准化的协议,专家人员和强大的支持性护理基础设施.
- 门诊AutoHCT和IEC计划的传播需要可行的建议和机构的承诺.
相关概念视频
Regulation of Hematopoietic Stem Cells
3.2K
All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a limited life span. In addition, many are depleted in immune surveillance or combatting an injury or infection. This makes blood one of the most regenerative tissues. Hematopoiesis helps replenish these blood and immune cells, restoring the body's normal functioning. However, overproduction of blood and immune cells can make them cancerous or...
3.2K
Multipotency of Hematopoietic Stem Cells
3.0K
The hematopoietic stem cells or HSCs are multipotent, meaning they can differentiate and give rise to all blood and immune cells. HSCs are maintained in the quiescent stage until an external stimulus initiates their differentiation. The multipotent HSCs exist as two heterogeneous populations, long-term repopulating cells (LTRC) and short-term repopulating cells (STRC). The two HSC populations have different surface markers or receptors and are classified based on quiescence and long-term...
3.0K
Stem Cell Therapy for Tissue Regeneration
4.0K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.0K
Bone Marrow Sampling and Transplants
317
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
317


