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Updated: Jun 27, 2026

Rapid One-step Enzymatic Synthesis and All-aqueous Purification of Trehalose Analogues
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内注射三糖可以减少α-synuclein的寡合体,并加速α-synuclein的聚合

Makoto T Tanaka1, Yasuo Miki1,2, Fumiaki Mori1

  • 1Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.

Brain communications
|August 21, 2024
PubMed
概括

通过减少有毒的α-synuclein (αSyn) 寡合体,trehalose的使用改善了多个系统缩的小鼠模型中的记忆力. 这种神经保护策略加速αSyn聚合,为这种神经退行性疾病提供了潜在的早期治疗方法.

关键词:
聚合方式 聚合方式 聚合方式鼻内注射 鼻内注射 鼻内注射多个系统缩.这是一种三糖.这是一种α-synuclein寡合体.

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