童年不良经历与中年和老年人认知功能轨迹的纵向关联:基于群体的轨迹建模
1School of Nursing, Shanxi Medical University, Taiyuan, China.
Frontiers in psychiatry
|August 21, 2024
概括
童年不良经历 (ACE) 不显示对认知功能的剂量反应影响. 然而,特定的ACE与不同的认知轨迹相关,为目标干预提供信息.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 公共卫生 公共卫生
背景情况:
- 众所周知,不良童年经历 (ACE) 会影响认知功能.
- 在ACE和认知功能轨迹之间的准确关系需要进一步阐明.
研究的目的:
- 识别与ACE相关的不同认知功能轨迹.
- 调查累积ACE和认知功能模式之间的相关性.
主要方法:
- 基于组的轨迹建模被用于识别认知衰退子组.
- 多项式无序后勤回归分析确定了影响因素.
主要成果:
- 确定了三个认知轨迹:低起点衰退,高起点稳定性和中起点衰退.
- 在累积ACE和认知功能之间没有发现剂量反应关系.
- 特定的ACE,如兄弟姐妹死亡,父母死亡,身体虐待和家庭暴力,与特定的认知轨迹有关.
结论:
- 虽然累积的ACE缺乏与认知衰退的剂量反应关联,但特定的ACE与认知轨迹有关.
- 将ACE整合到认知评估中可以帮助早期识别风险和个性化干预.
- 促进支持性环境对于优化认知功能至关重要,承认早期生活经验的影响.
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