心脏病发作位置和体积对患有急性岛内脑梗塞的老年患者认知功能障碍的影响
Fei-Fei Liang1, Xiao-Xia Liu1, Jiang-Hong Liu1
1Department of Geriatrics, Zhangjiakou First Hospital in Hebei Province, Zhangjiakou 075000, Hebei Province, China.
World journal of psychiatry
|August 21, 2024
概括
患有急性岛内脑梗塞的老年患者经历了较大的心脏病发作体积,特别是在基底和丘脑中,更容易发生认知功能障碍. 这些心脏病发作位置与认知得分有显著的负相关性.
科学领域:
- 神经学 神经学
- 老年病的医生 老年病的医生
- 放射学 放射学是一门学科.
背景情况:
- 全球人口老龄化,导致脑梗塞发病率上升.
- 脑梗塞,特别是在老年人中,与高死亡率和残疾率有关.
研究的目的:
- 研究心脏病发作位置和体积对患有急性岛屿性脑梗塞的老年人认知障碍的影响.
- 分析受心脏病发作影响的特定大脑区域与认知功能之间的关系.
主要方法:
- 一组98名患有急性岛内脑梗塞的老年患者被研究了6个月.
- 用蒙特利尔认知评估尺度 (MoCA) 评估认知功能.
- 磁共振成像 (MRI) 用于确定心脏病发作的体积和位置,比较有和没有认知障碍的患者.
主要成果:
- 患有认知障碍的患者心脏病发作量显著增加,特别是在基底腺和丘脑中.
- 基底,丘脑和混合病变中的心脏病发作量与MoCA得分有负相关性.
- 在这些特定区域中,较高的心脏病发作量与较差的认知结果密切相关.
结论:
- 基底,丘脑和混合性损伤区域的心脏病发作是急性岛屿性脑梗塞的老年患者认知功能障碍的关键预测因素.
- 较大的心脏病发作量与患上认知功能障碍的可能性更高相关.
- 该研究强调了心脏病发作位置和大小在决定认知结果中的关键作用.
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