单独患有双相情感障碍的患者的认知障碍与患有双相情感障碍与边缘性人格障碍并发症的患者相比
Chao-Min Wang1, Hua Xue1, Bo Xin1
1Department of Psychiatry, The First Hospital of Hebei Medical University, Shijiazhuang 050031, Hebei Province, China.
World journal of psychiatry
|August 21, 2024
概括
患有双相情感障碍 (BD) 和并发性边缘性人格障碍的患者表现出比单独患有BD的患者更大的认知障碍. 这突显了共患病对严重精神疾病中认知功能的重大影响.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 认知心理学 认知心理学
背景情况:
- 双极性障碍 (BD) 是一种严重的精神疾病.
- 与边缘性人格障碍 (BPD) 的并发症使BD表现和预后复杂化.
- 了解并发性BD和BPD的认知差异对于有针对性的干预至关重要.
研究的目的:
- 为了研究和比较BD和并发性BPD患者与单独BD患者的认知障碍.
- 确定受BD和BPD共患病影响的特定认知领域.
主要方法:
- 一项比较研究涉及80名患有BD和并发性BPD的患者 (A组),80名仅患有BD的患者 (B组) 和80名健康对照.
- 认知功能使用可重复电池评估神经心理状态 (RBANS),Stroop色词测试和韦克斯勒智力尺度修订 (WAIS-RC) 进行评估.
主要成果:
- 两个BD组 (A和B) 的认知指数明显低于健康对照组 (P<0.05).
- 与B组 (单独BD) 相比,A组 (BD + BPD) 在多个认知领域表现明显差.
- A组的具体缺陷包括即时记忆,视觉宽度,口语功能 (RBANS) 和口语/表现/整体智商 (WAIS-RC),以及Stroop测试中的反应时间较慢.
结论:
- 伴随性边缘性人格障碍在患有双相情感障碍的患者中显著加剧了认知障碍.
- 患有BPD的BD患者的认知缺陷比没有BPD的BD患者更为严重.
- 这些发现强调了评估和解决认知功能的重要性,用于治疗并发性BD和BPD.
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