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对2型糖尿病血红蛋白A1c降低的远程药剂师干预的评估在一个负责任的护理组织中
Emily C Nuttall1, Timothy Reynolds2, Ann D Kataria3
1Department of Pharmacy, Baylor Scott & White Health, Dallas, Texas, USA.
概括
远程临床药剂师干预可以显著改善2型糖尿病 (T2DM) 的成年人血红蛋白A1c (HbA1c). 接受药剂师建议导致HbA1c的降低比拒绝的更大.
科学领域:
- 药理学 药理学是指药理学的学科.
- 内分泌学 在内分泌学.
- 内部医学 内部医学
背景情况:
- 临床药剂师在门诊护理中非常有价值,特别是在2型糖尿病 (T2DM) 中降低血红蛋白A1c (HbA1c).
- 关于远程,基于转诊的药房程序对T2DM管理的临床有效性的数据有限.
研究的目的:
- 评估远程药剂师干预对T2DM患者血糖控制的影响.
- 评估接受与拒绝的药剂师建议对HbA1c水平的影响.
主要方法:
- 对T2DM患者 (HbA1c ≥8.5%) 的多中心,回顾性队列图表审查,用于药房药物评估.
- 主要结局:从基线到2-5个月后续的HbA1c的平均变化.
- 二次结果:使用美国糖尿病协会推的二次预防和血糖相关事件.
主要成果:
- 接受的药剂师干预措施在2-5个月的随访后,平均HbA1c降低了-2.7%.
- 被拒绝的药剂师干预表明,同期的平均HbA1c降低为-0.6%.
- 接受和拒绝的干预措施之间的HbA1c降低差异在统计学上是显著的 (P=0.0068).
结论:
- 远程药剂师干预显著改善了T2DM成年人的血糖控制.
- 初级保健提供者接受药剂师建议对于最大限度地提高治疗效益至关重要.
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