非结核性真菌菌的流行病学和实验室检测
Nuo Xu1, Lihong Li1, Shenghai Wu1,2
1The 4th Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Heliyon
|August 21, 2024
概括
在全球范围内,非结核性菌根菌 (NTM) 感染正在增加. 本综述详细介绍了中国的NTM流行病学,物种和先进的实验室检测方法,以改善临床诊断和治疗.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 临床诊断 临床诊断 临床诊断
背景情况:
- 全球非结核菌菌 (NTM) 感染的发病率正在上升.
- 传染 NTM 构成了重大的公共卫生挑战,需要更新流行病学数据和诊断策略.
- 了解NTM物种分布对于有效的治疗和感染控制至关重要.
研究的目的:
- 从2013年到2023年,系统地审查中国NTM分离物种的流行病学和物种分布.
- 评估各种NTM实验室检测方法的诊断准确性和临床影响.
- 提供有关NTM细菌学检测和商业上可用的识别工具包的进展的见解.
主要方法:
- 在PubMed,科学网,谷歌学者,CNKI和万芳数据库 (2013-2023) 的系统文献搜索.
- 对随机临床试验,元分析,系统评论和观察性研究的综合文献综述.
- 对流行病学数据,NTM物种分布和实验室检测方法的分析.
主要成果:
- 介绍了中国NTM分离物种的最新流行病学数据和物种分布.
- 讨论各种细菌学检测方法的优缺点.
- 突出了最近的进展和用于临床使用的商业Mycobacterium识别套件.
结论:
- 加强对中国的NTM流行病学和诊断的了解至关重要.
- 改进的实验室检测方法可以显著影响临床结果.
- 确定了NTM诊断和治疗的研究缺口和未来优先事项.
更多相关视频
相关概念视频
Pulmonary Tuberculosis IV
134
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
134
Pulmonary Tuberculosis III
316
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
316
Pulmonary Tuberculosis I
227
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
227
Pulmonary Tuberculosis II
215
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
215
Pulmonary Tuberculosis V
174
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
174


