程序前SYNTAX评分与Impella辅助高风险皮肤冠状动脉干预结果的关联
Giorgio A Medranda1, Haroon A Faraz2, Julia B Thompson3
1Division of Cardiology, NYU Langone Hospital-Long Island, Mineola, New York.
概括
复杂冠状动脉疾病患者中SYNTAX得分高的患者接受高风险皮肤冠状动脉干预 (HRPCI) 预测结果更差. 支持Impella并没有减轻主要心血管和脑血管不良事件 (MACCE) 的风险增加.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 医疗器械 医疗器械
背景情况:
- 患有复杂冠状动脉疾病 (CAD) 和高SYNTAX分数的患者接受皮肤冠状动脉干预 (PCI) 时面临较差的结果.
- 该SYNTAX I得分分层次化CAD复杂性,并预测PCI后的结果.
- 像Impella这样的机械循环支持 (MCS) 设备用于高风险的PCI (HRPCI).
研究的目的:
- 评估Impella MCS是否能减轻高SYNTAX I评分对HRPCI患者的不良预后影响.
- 评估SYNTAX I得分层和Impella辅助HRPCI后的临床结果之间的关系.
主要方法:
- 从PROTECT III研究中接受Impella辅助HRPCI的850名患者的回顾性分析 (2017年3月至2020年3月).
- 患者被分为低 (≤22),中等 (23-32) 和高 (≥33) 的SYNTAX I评分组.
- 使用多变量回归分析对90天内包括重大心血管和脑血管不良事件 (MACCE) 在内的结果进行了比较.
主要成果:
- 高的SYNTAX I得分与老年患者的年龄有关.
- 在对共变量进行调整后,高的SYNTAX I得分仍然是90天MACCE (HR 2.14,P<.01) 与低得分相比的显著预测指标.
- 与低得分相比,中间的SYNTAX I得分没有显著预测90天的MACCE (HR 0.92,P=.80).
结论:
- 在接受Impella辅助HRPCI的患者中,高的SYNTAX I得分独立预测90天MACCE的增加.
- 支持Impella似乎没有减轻高基线SYNTAX I得分的负面预后效应.
- 需要进一步调查以确定影响高风险人群结果的患者和程序因素.
更多相关视频
06:10Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
3.2K
05:41Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control
Published on: December 16, 2022
3.4K
相关概念视频
01:28Cardiac Catheterization I: Pre-Procedure Overview
3.4K
Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
3.4K
01:30Acute Coronary Syndrome III: Diagnostic Studies
500
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
500