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Updated: Jun 16, 2025

Extremely Rapid and Specific Metabolic Labelling of RNA In Vivo with 4-Thiouracil Ers4tU
00:11

Extremely Rapid and Specific Metabolic Labelling of RNA In Vivo with 4-Thiouracil Ers4tU

Published on: August 22, 2019

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鲁德S:细菌脱硫酶负责tRNA4-thiouridine去修改的细菌脱硫酶

Rapolas Jamontas1, Audrius Laurynėnas2, Deimantė Povilaitytė1

  • 1Department of Molecular Microbiology and Biotechnology, Institute of Biochemistry, Life Sciences Center, Vilnius University, 10257 Vilnius, Lithuania.

Nucleic acids research
|August 21, 2024
PubMed
概括

RudS酶从细菌tRNA中去除4-thiouridine (s4U) 修饰,影响在UVA光下生长. TudS域催化了这一过程,而DUF1722则有助于tRNA结合,这表明它在 prokaryotic 应激反应中的作用.

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