药物诱导的睡眠内镜预测了腺切除术的主观结果
Derek J Lam1, Andrea Hildebrand2, Thuan Nguyen2
1Department of Otolaryngology-Head and Neck Surgery, Oregon Health and Science University, Portland, Oregon, U.S.A.
The Laryngoscope
|August 21, 2024
概括
在腺切除术 (AT) 后持续阻塞性睡眠呼吸暂停 (OSA) 是常见的. 药物诱导睡眠内镜 (DISE) 可以预测结果,肥胖,男性性别和多层次阻塞表明结果较差.
科学领域:
- 儿科耳鼻喉科 儿科耳鼻喉科
- 睡眠医学 睡眠医学
- 手术结果研究研究.
背景情况:
- 持久性阻塞性睡眠呼吸暂停 (OSA) 影响20-30%的儿童在腺切除术 (AT) 后.
- 确定治疗成功的预测因素对于管理儿科睡眠呼吸障碍 (SDB) 至关重要.
- 药物诱导睡眠内镜 (DISE) 评估睡眠期间的呼吸道崩.
研究的目的:
- 评估在AT期间执行的DISE对主观结果的预测能力.
- 为了确定与儿童在AT后持续的OSA症状相关的因素.
主要方法:
- 194名儿童 (2-18岁) 接受SDB的AT的前性队列研究.
- 包括有AT衰竭的危险因素 (例如,年龄大于7岁,肥胖,严重的OSA) 的儿童.
- DISE与AT同时进行;多变量回归分析了AT后PSQ和OSA-18分数的预测因素.
主要成果:
- 在AT后观察到儿科睡眠问卷 (PSQ) 和OSA-18分数的显著改善 (p < 0.001).
- 最常见的阻塞部位包括桃体,鼻呼吸道,腺体和鼻.
- 更糟糕的主观结果与肥胖,男性性别和多层次阻塞 (鼻腔气道,舌头底部,腺) 有关.
结论:
- 持久性OSA和症状负担仍然是AT后风险儿童的常见挑战.
- DISE的发现,特别是涉及鼻气道和舌头底部的多层次阻塞,预测主观结果较差.
- 肥胖和男性性别也是AT后结果更差的重要预测因素.
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