在牛皮患者的Helicobacter pylori感染及其与牛皮严重程度的关系:横截面研究
Soheir Abdel-Hamid1, Shimaa Arafat Abdel-Monem2
1Dermatology, Venereology and Andrology, Faculty of Medicine, South Valley University, Qena, Egypt.
牛皮患者的Helicobacter pylori (H. pylori) 感染率高于健康人群. 然而,H. pylori感染似乎没有影响牛皮的严重程度.
科学领域:
- 皮肤病学 皮肤病学
- 传染性疾病 传染性疾病
- 胃肠病学 胃肠病学
背景情况:
- 牛皮是一种常见的炎症性皮肤疾病,有各种潜在的原因.
- 正在探索Helicobacter pylori (H. pylori) 感染作为可能导致牛皮病病因的因素.
研究的目的:
- 为了比较患有牛皮的患者和健康的对照人群中H. pylori感染的流行率.
- 为了调查牛皮的严重程度和H.pylori感染的存在之间的任何相关性.
主要方法:
- 进行了一项横截面研究,涉及牛皮患者和对照组.
- 使用H.pylori便抗原-酶相关的免疫吸收试验 (HpSA-ELISA) 来检测H.pylori感染在两组.
- 牛皮的严重程度是使用牛皮严重程度指数 (PASI) 评分来评估的.
主要成果:
- 与对照组 (30.66%) (p=0.046) 相比,在牛皮患者 (45.33%) 中观察到明显更高的H. pylori感染患病率.
- 在牛皮患者中,没有发现H. pylori感染与PASI得分,年龄或疾病持续时间之间的显著相关性.
- 牛皮和对照组参与者的平均年龄相似 (约37岁).
结论:
- 患有牛皮的患者表现出H.pylori感染的更高患病率.
- 杆菌感染似乎不是牛皮病严重程度的决定因素.
更多相关视频
09:05High Resolution Electron Microscopy of the Helicobacter pylori Cag Type IV Secretion System Pili Produced in Varying Conditions of Iron Availability
Published on: November 21, 2014
02:28Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
Published on: March 1, 2024
相关概念视频
Peptic Ulcer Disease I: Introduction
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy
Pathophysiology of Peptic Ulcer Disease: Injurious Factors
In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds...
Pathophysiology of Peptic Ulcer Disease: Mucosal Defense Factors
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Peptic Ulcer Disease II: Pathophysiology
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.
