生活必需品8及其与骨关节炎和残疾的关联:基于NHANES 2005-2018数据库的横截面研究
Mi Chen1,2, Yuebai Chen3, Chao Li4
1Department of Physical Medicine and Rehabilitation, Xiangya Hospital of Central South University, Changsha, Hunan, China.
概括
通过Life's Essential 8 (LE8) 改善心血管健康与骨关节炎患者的残疾减少有关. 较高的LE8分数与更好的身体功能相关,并且OA患者的限制较少.
科学领域:
- 心血管健康 心血管健康
- 骨关节炎研究 骨关节炎研究
- 关于残疾人的研究.
背景情况:
- 骨关节炎 (OA) 经常与心血管疾病 (CVD) 风险因素同时发生.
- 这种并发症加剧了OA症状和功能限制.
- 了解心血管健康和OA残疾之间的相互作用至关重要.
研究的目的:
- 调查生活必需品8 (LE8) 与OA患者的残疾之间的关联.
- 为了确定更好的心血管健康是否与OA患者的残疾减少有关.
主要方法:
- 使用2005-2018年国家健康和营养检查调查 (NHANES) 数据对8334名美国成年人 (≥20岁) 进行横截面研究.
- 对于心血管健康 (CVH) 类别 (低,中等,高) 的LE8组件 (饮食,体力活动,尼古丁暴露,睡眠,BMI,脂质,葡萄糖,BP) 获得0-100分.
- 通过身体功能问卷评估残疾;用于关联分析的多变量逻辑回归.
主要成果:
- 在CVH得分增加10个点与15%较低的OA患病率有关.
- 患有OA的人患残疾的可能性是OA的两倍多.
- 与低CVH水平 (P<0.05) 相比,高CVH水平显著降低了各种领域 (例如日常生活活动) 的残疾患病率.
- 身体质量指数 (BMI),体力活动 (PA) 和睡眠健康与所有领域的残疾有关;血脂没有.
结论:
- 对LE8指南的更高遵守与OA患者身体功能障碍的患病率降低有关.
- 改善心血管健康可以减轻骨关节炎患者的功能限制.
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