为卡塔尔定制的胎儿生长和出生体重标准:基于人口的队列研究
Thomas Farrell1,2,3, Fathima Minisha1, Najat Khenyab1,4
1Department of Obstetrics and Gynecology, Women's Wellness and Research Centre, 36977 Hamad Medical Corporation , Doha, Qatar.
Journal of perinatal medicine
|August 21, 2024
概括
定制的出生体重图表可以提高小 (SGA) 和孕期大 (LGA) 婴儿的检测. 这项研究从卡塔尔注册数据中提取了系数来创建这些图表,与现有标准相比,提高了诊断准确度.
科学领域:
- 围产医学和产科 围产医学和产科
- 胎儿生长和发育 胎儿生长和发育
- 公共卫生和流行病学
背景情况:
- 现有的基于人口的出生体重标准可能会错误地分类胎儿生长异常.
- 定制的出生体重百分比可以更好地检测妊娠年龄小 (SGA) 和妊娠年龄大 (LGA) 的婴儿.
- 开发特定区域的增长图表对于对不同人口的准确评估至关重要.
研究的目的:
- 为卡塔尔人口定制的出生体重增长图表推导系数.
- 为了改善卡塔尔SGA和LGA新生儿的识别.
- 量化影响卡塔尔怀孕中出生体重的宪法和病理因素.
主要方法:
- 采用PEARL注册 (2017-2018) 的数据,用于卡塔尔分娩的妇女.
- 开发了一种多变量线性回归模型来预测最佳出生体重.
- 包括生理变量 (妊娠年龄,母亲身高/体重,种族,性别,婴儿性别) 和排除病理变量 (高血压,糖尿病,吸烟) 以获得最佳体重.
主要成果:
- 预测卡塔尔母亲出生时的最佳体重为3,235g,其特征均值.
- 影响出生体重的重要宪法因素包括妊娠年龄,母亲的身高,体重和性别平等.
- 定制的百分位标识了SGA和LGA分别为11.1%和12.2%的利率,与哈德洛克 (SGA 26.3%,LGA 1.8%) 和芬顿 (SGA 12.9%,LGA 4.0%) 标准形成鲜明对比.
结论:
- 宪法和病理因素在卡塔尔显著影响胎儿生长和出生体重.
- 量化变异允许生成定制图表,以更好地识别异常生长.
- 当前的人口标准可能导致SGA和LGA在卡塔尔产妇人口中的错误诊断.
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