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Updated: May 4, 2026

Improved Generation of Induced Cardiomyocytes Using a Polycistronic Construct Expressing Optimal Ratio of Gata4, Mef2c and Tbx5
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Improved Generation of Induced Cardiomyocytes Using a Polycistronic Construct Expressing Optimal Ratio of Gata4, Mef2c and Tbx5

Published on: November 13, 2015

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产生四种不同的同位素细胞系,在I频段或A频段的缩变体中产生四种不同的同位素细胞系

Hanne M Boen1, Bert Vandendriessche2, Jolien Schippers2

  • 1University of Antwerp and Antwerp University Hospital, GENCOR, Cardiovascular Research, Belgium; University of Antwerp, GENCOR, Center of Medical Genetics, Belgium.

Stem cell research
|August 21, 2024
PubMed
概括

TTN (TTNtv) 中的截断变体会影响异常扩展性心肌病风险. 靠近的I频段TTNtv (TTNtvI) 比远端的A频段TTNtv (TTNtvA) 具有较低的致病性,如患者衍生干细胞模型所示.

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