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Updated: Jun 15, 2025

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
08:22

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Published on: December 1, 2017

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新兴的X链基因与女性神经发育障碍相关

Jeronimo Lukin1, Corinne M Smith2, Silvia De Rubeis1

  • 1Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; The Alper Center for Neural Development and Regeneration, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

Current opinion in neurobiology
|August 21, 2024
PubMed
概括

与X相关的基因对神经发育障碍 (NDD),如智力障碍 (ID) 和自闭症谱系障碍 (ASD) 产生重大贡献. 本综述侧重于X链接遗传学和神经生物学,特别是女性,以了解NDD风险.

关键词:
一个X染色体是X染色体.一个X染色体不活化.在X-Y对.自闭症谱系障碍 自闭症谱系障碍智力障碍 智力障碍是一种智力障碍.神经发育的神经发育性别差异的性别差异.

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