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通过将异质基因组数据集成到贝叶斯框架中,准确识别与大脑疾病相关的基因

Dan He1, Ling Li1, Huasong Zhang1

  • 1Department of Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510006, China; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangzhou, 510006, China.

EBioMedicine
|August 21, 2024
PubMed
概括

一个新的框架,iGOAT,通过整合遗传和表观遗传数据来识别脑疾病风险基因. 这种方法预测了新的风险基因,促进了对神经和精神疾病的理解和治疗发展.

关键词:
贝叶斯的框架 贝叶斯的框架增强者 促进者 互动 互动全基因组关联研究研究.神经退行性/神经系统疾病精神疾病 精神疾病风险基因 风险基因 风险基因SNP与SNP之间的相互作用

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