相关实验视频
Updated: Jun 15, 2025

07:52
In Vivo Wireless Optogenetic Control of Skilled Motor Behavior
Published on: November 22, 2021
3.3K
运动皮层负责状体的运动动力学和熟练和不熟练行动的执行
Mark A Nicholas1, Eric A Yttri2
1Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15213, USA; Center for the Neural Basis of Cognition, Carnegie Mellon University and University of Pittsburgh, Pittsburgh, PA 15213, USA.
Neuron
|August 21, 2024
概括
运动皮质对于启动运动和条状运动活动至关重要. 运动皮层的损伤会损害运动,导致持续的缺陷,即使一些功能恢复.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 系统神经科学 系统神经科学
背景情况:
- 条纹体和运动皮质对于选择和执行自愿运动至关重要.
- 这些大脑区域在指导运动中的确切相互作用仍然不清楚.
研究的目的:
- 研究运动控制中的运动皮质和条纹体的神经和行为贡献.
- 了解运动皮层病变如何影响条状皮质活动和运动性能.
主要方法:
- 小鼠运动皮层的双边病变.
- 每天记录条纹活动和达到损伤后的性能.
- 控制的是头顶皮层的病变.
主要成果:
- 运动皮层病变导致了立即达到障碍,并取消了条状运动活动.
- 状体投射和内部神经动力学无法恢复,进入非运动编码状态.
- 受伤的小鼠表现出无法切换运动计划,类似于步态结 (FOG).
结论:
- 运动皮层是产生训练有素和未训练有素的行动所必需的.
- 排骨运动动力学严重依赖于运动皮层的输入.
- 运动皮层的完整性对于保持运动控制和预防FOG等缺陷至关重要.
相关概念视频
Direct Motor Pathways
1.9K
The direct motor pathways, also known as the pyramidal tracts, are a group of neural pathways that originate in the brain and descend through the spinal cord. They control the voluntary movement of the body. There are two major direct motor pathways: the corticospinal and the corticobulbar tracts.
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and...
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and...
1.9K
Motor and Sensory Areas of the Cortex
3.6K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
3.6K
Hierarchy of Motor Control
2.6K
The hierarchy of motor control refers to the different levels of organization and processing involved in controlling movement in the body. These levels range from higher cortical areas involved in planning and decision-making to lower spinal cord reflexes that respond automatically to external stimuli.
2.6K
Somatosensory, Motor, and Association Cortex
449
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
449
Indirect Motor Pathways
1.4K
The indirect motor or extrapyramidal pathways originate in the brainstem, the lower portion of the brain that connects it to the spinal cord. They consist of several distinct tracts, each with specialized functions. The four main tracts of the indirect motor pathways are the vestibulospinal tract, the reticulospinal tract, the tectospinal tract, and the rubrospinal tract.
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...
1.4K
Brainstem
1.9K
The brainstem, located inferior to the brain and superior to the spinal cord, serves as a bridge between the cerebrum and the spinal cord. It plays a vital role in relaying information and controlling critical life functions. It comprises three primary regions: the midbrain, pons, and medulla oblongata.
The Midbrain
The midbrain is located beneath the diencephalon and connects the cerebrum with the lower parts of the brain. The cerebral peduncles are prominent midbrain structures that house the...
The Midbrain
The midbrain is located beneath the diencephalon and connects the cerebrum with the lower parts of the brain. The cerebral peduncles are prominent midbrain structures that house the...
1.9K

