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Updated: Jun 15, 2025

A High-content Assay for Monitoring AMPA Receptor Trafficking
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在阿尔茨海默氏病中,KEAP1/PGAM5/AIFM1-介导的氧化死途径

Fuxin Zhong1, Lei Xiong1, Jiani Wu1

  • 1Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, PR China.

Brain research
|August 21, 2024
PubMed
概括

这项研究揭示了KEAP1/PGAM5/AIFM1通路在阿尔茨海默病 (AD) 模型中驱动神经元细胞死亡. 准这种氧化亡途径可能为神经退行症提供新的治疗策略.

关键词:
一个AIFM1一个AIFM1.阿尔茨海默氏症是阿尔茨海默氏症的疾病.这就是KEAP1的意义.氧化性亡症 (Oxeiptosis) 是一种氧化压力是一种氧化压力.这是一个PGAM5PGAM5.

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