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Updated: Jun 15, 2025

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
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Published on: June 6, 2025

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在多发性骨髓瘤中,需要SAGA乙转移酶模块来维持MAF和MYC瘤基因表达程序

Ying-Jiun C Chen1,2, Govinal Badiger Bhaskara3,2, Yue Lu3,2

  • 1Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA; ychen38@mdanderson.org sroth@mdanderson.org sharonrothdent@gmail.com.

Genes & development
|August 21, 2024
PubMed
概括

研究人员确定了SAGA复合体的组成部分ADA2B,作为多发性骨髓瘤 (MM) 细胞生长的关键调节者. 准ADA2B及其相关途径为这种无法治愈的癌症提供了潜在的新疗法策略.

关键词:
在 ADA2B 中.在MAF中,MAF是MAF.我的世界 MYC萨加复合体 (SAGA) 是一个复合体.这是一个SANT域名.多发性骨髓瘤是多发性骨髓瘤的一种.致癌的基因表达程序是致癌的.

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