[废水处理过程中的生物气溶抗生素耐药性的分析]
Tang Yang1, Xu-Yi Wang1, Xin Sui1
1School of Environmental and Municipal Engineering, Qingdao University of Technology, Qingdao 266520, China.
Huan jing ke xue= Huanjing kexue
|August 21, 2024
概括
污水处理厂释放抗生素耐药基因和细菌到空气中,造成健康风险. 废水是这些空气污染物的主要来源,突出了需要更好地控制污染.
科学领域:
- 环境微生物学环境微生物学
- 分子生物学分子生物学
背景情况:
- 污水处理厂 (WWTP) 是抗生素耐药基因 (ARG) 和致病性抗生素耐药细菌 (PARB) 的潜在来源.
- 从WWTPs排放的生物气溶可以促进ARG和PARB在周围环境中的传播.
- 了解空中ARG和PARB的流行率和来源对于风险评估和公共卫生保护至关重要.
研究的目的:
- 调查来自WWTPs的生物气溶中的ARG和PARB的流行率和来源.
- 描述生物气溶和相关废水的抗生素耐药性.
- 为了识别从WWTP单元中轻松喷雾的特定PARB.
主要方法:
- 使用元基因组测序和组装来分析生物气溶和废水的抗体.
- 在不同空气样本 (上风,下风,内部WWTP位置) 中对ARG亚型和PARB丰度的定量分析.
- 鉴定与ARG和气溶化潜力相关的特定细菌物种.
主要成果:
- 与上风样本相比,在WWTP和下风的生物气溶中检测到ARG和PARB的丰度和多样性更高.
- 多种药物耐药性基因是主要的ARG类型,macB是最普遍的亚型.
- 废水被确定为生物气溶ARG和PARB的主要来源,特别是来自气化和污泥排水装置的废水.
- 确定了37种多药耐药PARB,其中32种,包括Pseudomonas aeruginosa和Escherichia coli,显示出高的气溶潜力.
结论:
- WWTP生物气溶对ARG和PARB的传播做出了重大贡献.
- 废水废水和特定处理装置是空气传播抗生素耐药性的关键来源.
- 这些发现为评估健康风险和制定对抗生素耐药性污染的缓解策略提供了关键数据.
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