在合成气体发酵中合成生物学方法和生物分离
Naorem Bela Devi1, Gopal Pugazhenthi2, Kannan Pakshirajan1
1Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati 781039, Assam, India.
Trends in biotechnology
|August 21, 2024
概括
生物质气化产生合成气,用于发酵制成有价值的化学品. 本综述探讨了微生物工程和技术的进步,以克服可持续化学生产的规模化挑战.
科学领域:
- 生物技术和生物工程 生物技术和生物工程
- 环境科学 环境科学
- 化学工程是化学工程的重要组成部分.
背景情况:
- 化石燃料的依赖推动了温室气体排放和气候变化.
- 生物质气化提供了一个可持续的替代方案,生产合成气 (H2和CO).
- 通过Wood-Ljungdahl路径发酵合成气,在温和条件下将合成气转化为有价值的化学物质.
研究的目的:
- 审查合成气发酵技术的进展.
- 为了应对扩大合成气发酵过程的挑战.
- 探索使用遗传工具和代谢工程用于乙原体和非模型生物.
主要方法:
- 关于合成气发酵的科学文献的综述.
- 对遗传工具和代谢工程策略的分析.
- 检查用于菌株发展的启用技术.
- 评估挑战,包括合成气组成的变化和污染.
主要成果:
- 基因工具和代谢工程的进步扩大了从合成气发酵到产品范围.
- 启用技术加速了乙原体和其他非模型生物的菌株开发.
- 涵盖的关键领域包括微生物,气体成分影响,分离技术,技术经济分析和商业化.
结论:
- 合成气发酵为可持续化学品生产提供了一个有前途的途径.
- 克服规模化挑战需要在微生物工程和工艺技术方面取得进一步的进步.
- 本综述提供了一个全面的概述,以指导未来的研究和商业化努力.
相关概念视频
Synthetic Biology
4.7K
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
Golden rice
Golden rice is a genetically modified...
4.7K
Bioremediation
18.2K
Bioremediation is the use of prokaryotes, fungi, or plants to remove pollutants from the environment. This process has been used to remove harmful toxins in groundwater as a byproduct of agricultural run-off and also to clean up oil spills.
18.2K
Fates of Pyruvate
8.4K
Pyruvate is the end product of glycolysis, where glucose is oxidized to pyruvate, simultaneously reducing NAD+ to NADH. Two molecules of ATP are also produced by substrate-level phosphorylation.
In aerobic organisms, pyruvate is metabolized via the citric acid cycle to produce reduced coenzymes NADH and FADH2. These coenzymes are then oxidized in the electron transport chain to produce ATP and, in the process, regenerate the NAD+ and FAD. As seen in some cell types and organisms, fermentation...
In aerobic organisms, pyruvate is metabolized via the citric acid cycle to produce reduced coenzymes NADH and FADH2. These coenzymes are then oxidized in the electron transport chain to produce ATP and, in the process, regenerate the NAD+ and FAD. As seen in some cell types and organisms, fermentation...
8.4K


