在COVID-19前和COVID-19期间的早期青春期的差异:一个元分析
Nam Nhat Nguyen1,2, Tri Dang Do3,4, Hieu Hong Truong5
1Endocrinology Clinic, Hanh Phuc International Hospital, Binh Duong 75207, Vietnam.
American journal of epidemiology
|August 21, 2024
概括
随着COVID-19的流行,儿童早期青春期 (PP) 的风险显著增加. 这种情况发生在流行后的较年轻年龄,突出显示了儿科内分泌学中令人担忧的趋势.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- COVID-19 流行病已与儿童的各种健康变化有关.
- 早期青春期 (PP) 是一种儿童比预期更早进入青春期的情况.
研究的目的:
- 分析COVID-19爆发后早期青春期 (PP) 的发生率趋势.
- 调查在疫情期间与PP相关的表现时的年龄和身体质量指数 (BMI) SD分数 (SDS) 等因素.
主要方法:
- 对32项涉及24,200名参与者的研究进行了系统性审查和元分析.
- 疫情前和期间PP发病率,BMI SDS和呈现时的年龄的比较.
- 探索时间和PP风险之间的剂量反应关系.
主要成果:
- 在大流行期间观察到PP的几率显著增加 (OR = 1.96).
- 在大流行开始后,儿童在较年轻时接受了PP.
- 体重指数BMI SDS没有显示出大流行前和大流行期间之间的显著差异.
结论:
- COVID-19 流行病与转诊儿童中早熟青春期的发生率增加和早期发作有关.
- 需要进一步的研究来了解长期影响和潜在机制.
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