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Updated: Jun 15, 2025

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通过增量学习和异常检测来适应纳米孔测序基调模型的修改检测

Ziyuan Wang1, Yinshan Fang2, Ziyang Liu1,3

  • 1Department of Pharmacy Practice and Science, University of Arizona, Tucson, AZ, USA.

Nature communications
|August 21, 2024
PubMed
概括

本研究介绍了一种机器学习管道,用于使用纳米孔测序检测核酸修饰. 该方法可以准确地识别单分子和单核酸分辨率的修饰,即使在复杂的生物样本中也是如此.

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