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Updated: Jun 15, 2025

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来自瘤的RHOA突变物与GDP-bound状态中的效应物相互作用

Yuan Lin1, Theresa A Ramelot2, Simge Senyuz3

  • 1Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. yuan.lin@cchmc.org.

Nature communications
|August 21, 2024
PubMed
概括

在RHOA (Ras homolog家族成员A) 中的功能获取突变加快了其活动,使得即使在GDP-bound状态下,效应因子相互作用也能够促进癌症的发展.

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