在住院COVID-19患者中影响不同妄亚型的因素的探索:一个多中心的横截面研究
Xinrui Zhang1, Wei Zhu1, Cong Wang1
1Department of Evidence-Based Nursing Research Laboratory, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu, China.
Scientific reports
|August 21, 2024
概括
在COVID-19患者中,狂妄症亚型与特定因素有关. 营养不良和低白蛋白表明低活性和混合妄想的风险更高,而炎症在亚型中是关键.
科学领域:
- 医学研究 医学研究
- 传染性疾病 传染性疾病
- 老年病的医生 老年病的医生
背景情况:
- 痴呆症是COVID-19的重要并发症,影响患者的治疗结果.
- 影响COVID-19妄想严重程度的因素尚不清楚.
- 了解妄的亚型对于有针对性的干预至关重要.
研究的目的:
- 在COVID-19患者中识别与不同妄亚型相关的因素.
- 分析患者特征与妄想表现之间的关系.
主要方法:
- 在7个中国地点对1774名成年COVID-19住院患者 (2023年1月至2月) 进行了回顾性研究.
- 使用混评估方法和里士满兴奋镇静量表来评估妄想.
- 通过多变量分析分析了实验室数据和患者信息.
主要成果:
- 与年龄相关的低活性狂妄症,血清白蛋白水平低,虚弱,肉症和营养状况.
- 与年龄,D-二次体,肉症和营养状况相关的混合妄想.
- 过度活动妄想与年龄,前素,虚弱和健康状况相关.
结论:
- 营养状况不佳和低白蛋白预测COVID-19患者的低活性/混合妄想风险.
- 炎症标志物在妄亚型中具有相关性,突出显示了炎症的作用.
- 对痴呆症的临床警是必不可少的,特别是在患有炎症疾病的患者中.
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