对于接受急性缺血性中风内血管血栓切除术的老年患者,有利的功能结果的预测因素
Qingjia Liang1,2, Mingzhu Feng1, Milagros Galecio-Castillo3
1Department of Neurology and Advanced National Stroke Center, Foshan Sanshui District People's Hospital, Foshan, Guangdong Province, China.
European journal of medical research
|August 21, 2024
概括
经过机械血栓切除术 (MT) 的患有大血管闭塞急性缺血性中风 (LVO-AIS) 的老年患者在心房动史中表现更好. 较高的NIHSS得分预测,在接受MT的LVO-AIS患者中,结果会更差.
科学领域:
- 神经学 神经学
- 干预神经病学 干预神经病学
- 老年人中风医学 老年人中风医学
背景情况:
- 大血管封闭性急性缺血性中风 (LVO-AIS) 影响老年人,需要像机械血栓切除 (MT) 这样的有效治疗方法.
- 预测这种脆弱人群的功能结果对于指导治疗决策和管理期望至关重要.
研究的目的:
- 在老年患者 (≥80岁) 中,以MT治疗的LVO-AIS,确定有利的功能结果 (修改的兰金尺度0-2在90天) 的预测因素.
- 分析影响LVO-AIS的MT后恢复的人口,临床和程序因素.
主要方法:
- 使用中国中风大数据观测站 (BOSC) 数据库进行的回顾性观察研究.
- 纳入标准:年龄≥80,基线mRS 0-2,NIHSS>6,ASPECTS>6,MT在24小时内.
- 多变量回归分析以确定90天功能结果的预测因素.
主要成果:
- 前庭动病史与有利的功能结果的可能性更高相关 (OR2.09,p=0.012).
- 较高的基线国家卫生研究院中风量表 (NIHSS) 评分与不太有利的结果有关 (OR 0.64,p=0.007).
- 一个趋势表明,较高的基线阿尔伯塔中风计划早期CT得分 (ASPECTS) 可能与更好的结果相关 (p=0.065).
结论:
- 前庭动和较低的基线NIHSS是接受MT的老年LVO-AIS患者功能恢复的积极预测指标.
- 这些发现强调了考虑特定的临床因素对于预测这个患者群体的结果的重要性.
- 进一步的研究可能会阐明MT结果中的并发症和中风严重程度之间的复杂相互作用.
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