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Updated: Jun 15, 2025

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
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Published on: March 31, 2019

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通过与线粒体平衡相关的TFAM/cGAS-STING信号轴,CKIP-1静音抑制抑制OSCC

Ji-Rong Xie1, Xiao-Jie Chen1,2, Gang Zhou1,2

  • 1State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School and Hospital of Stomatology, Wuhan University, Wuhan, China.

Journal of cellular and molecular medicine
|August 22, 2024
PubMed
概括

抑制氨酸激酶2相互作用蛋白1 (CKIP-1) 抑制口腔状细胞癌 (OSCC) 的生长. 这通过线粒体转录因子A (TFAM) /cGAS-STING通路发生,为OSCC提供了潜在的治疗点.

关键词:
基因治疗的基因疗法线粒体中的线粒体.口腔状细胞癌的癌症.信号传导的信号传导.

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