在尼泊尔人口中不育夫妇中男性的细菌精子
Anima Shrestha1,2, Dev Raj Joshi1, Dijan Vaidya3
1Central Department of Microbiology, Institute of Science and Technology, Tribhuvan University, Kathmandu, Nepal.
Systems biology in reproductive medicine
|August 22, 2024
概括
在尼泊尔,25.3%的不孕男性中发现了精液中的细菌感染 (细菌精液). 这种感染与精液量减少有关,可能导致男性不孕.
科学领域:
- 生殖医学 生殖医学
- 安德罗学与人类学
- 微生物学 微生物学
背景情况:
- 男性不孕症是一个重大问题,尿路感染是已知的促成因素.
- 精液中的细菌存在可能会对男性生育潜力产生负面影响.
研究的目的:
- 确定尼泊尔不育男性的精液细菌感染 (细菌精子症) 的患病率.
- 调查细菌精子和影响生育能力的关键精液参数之间的关联.
主要方法:
- 在13个月内 (2021年6月至2022年7月) 分析了来自不育男性的217个精液样本.
- 精液参数分析遵循世卫组织2021年指导方针.
- 使用基于培养的方法检测细菌的微生物学评估.
主要成果:
- 在分析的精液样本中有25.3%检测到细菌精子.
- 黄金葡萄球菌 (Staphylococcus aureus) 是最常见的细菌.
- 在带有细菌精子的样本中观察到精液体积的统计显著减少 (p=0.001).
- 虽然其他参数,如精子度,运动性,形态和活力显示出负面趋势,但在95%置信区间中,这些关联在统计学上并不显著.
结论:
- 在尼泊尔的不孕男性中,精液的细菌感染很常见.
- 精液参数受损部分与细菌感染有关,这表明细菌精液是男性不孕症的潜在原因.
- 这些发现为进一步研究本种群中精液细菌感染提供了基线.
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