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Updated: Jun 15, 2025

Author Spotlight: Understanding Dynamic Cellular Behaviors in Adult Mouse Dental Tissue Renewal and Repairment
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通过mTOR信号通路控制牙纸干细胞衰老

Lu Chen1, Xiping Wang2, Sha Tian3

  • 1Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Oral Diseases Shanghai Key Laboratory of Stomatology and Shanghai Research Institute of Stomatology, Shanghai 200011, People's Republic of China.

Stem cells (Dayton, Ohio)
|August 22, 2024
PubMed
概括

衰老会影响人类牙髓干细胞 (HDPSCs) 的再生. 使用OSU-T315针对ILK/AKT/mTOR/STAT1通路,可以使老年HDPSC复苏,并增强骨再生.

关键词:
在HDPSCs中使用.这是一个很好的例子. ILK ILK细胞衰老 细胞衰老骨质发生过程 (osteogenesis)蛋白质基质的保护性

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