在一个有尿路结石的年轻成年人中发生的 Actinotignum schaalii pyelonephritis:病例报告
Jayaweera Arachchige Asela Sampath Jayaweera1, Gerard Ranasinghe2
1MBBS, PG Dip in Med Micro, MSc-Bio Stat, MPhil, MD in Micro, DipFRCPath (UK), Senior Lecturer and Specialist Microbiologist, Department of Microbiology, Faculty of Medicine and Allied Sciences Rajarata University of Sri Lanka Saliyapura 50008, Sri Lanka.
Germs
|August 22, 2024
概括
一种新兴的尿路病原体Actinotignum schaalii,由于无氧生长,很难识别. 新型诊断平台和尿液格拉姆染色可以帮助其检测和治疗.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 临床诊断 临床诊断 临床诊断
背景情况:
- 阿克蒂诺蒂格纳姆·斯卡利 (Actinotignum schaalii) 是一种格拉姆阳性菌,是人类正常微生物群的一部分.
- 它被认为是一种新兴的病原体,主要是导致老年人尿路感染.
- 鉴定中的困难源于其无氧生长的要求和使用常规方法对其致病潜力的理解有限.
研究的目的:
- 报告一个年轻男性感染A. schaalii的病例.
- 突出诊断挑战和A. schaalii识别的潜在解决方案.
- 讨论抗菌素敏感性和治疗考虑因素.
主要方法:
- 一个24岁的男性患有炎炎和尿道结石的病例被介绍.
- 使用有氧和无氧瓶进行血液和培养的分析.
- 鉴定使用VITEK 2和MALDI-TOF分析进行.
- 16s DNA 分析用于尿路结算.
主要成果:
- 从无氧血培养和中成功分离了A. schaalii.
- 这位患者出现了发烧,侧侧疼痛和失尿症,被诊断为肌炎.
- 用皮佩拉西林-塔扎巴克坦治疗,然后用多西环素治疗,导致临床改善.
结论:
- 尿液Gram染色和厌氧介质对于检测A. schaalii.至关重要.
- 先进的诊断平台对于准确的病原体物种化至关重要.
- 缺乏病原体特定的断点使抗微生物敏感性解释和治疗决策复杂化.
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