关于优化压力的试点研究,用于标准化毛细血管补充时间测量
Zi-Yu Ma1, Shen Sun1, Shui-Cai Wu1
1Faculty of Environment and Life, Beijing University of Technology, China, No. 100 Pingleyuan, Chaoyang District, Beijing, 100124, China.
Heliyon
|August 22, 2024
概括
优化压力是精确的毛细血管补充时间 (CRT) 测量在败血症的关键. 施加10.0N-10.5N的力确保最可靠和一致的CRT读数.
科学领域:
- 生物医学工程 生物医学工程
- 身体生理学 身体生理学
- 关键护理医学 关键护理医学
背景情况:
- 毛细血管补充时间 (CRT) 测量对于评估诸如败血症和败血性休克等疾病越来越重要.
- 标准化CRT测量需要了解施加压力的影响.
- 以前的方法缺乏标准化的压力应用,可能会影响准确性.
研究的目的:
- 为了确定标准化毛细血管补充时间 (CRT) 测量的最佳压力.
- 分析不同压力水平对CRT读数的影响.
- 在临床环境中建立可靠的CRT评估协议.
主要方法:
- 17名健康志愿者参加了手指尖CRT测试.
- 施加力的范围从0.5N到10.5N,逐渐增加0.5N.
- 摄影光电显微镜 (PPG) 捕获光强度波动;一个专门的算法衍生CRT.
主要成果:
- 在21个压力级别 (p < 0.0001) 中观察到CRT的显著差异.
- 在4.5N和10.5N之间的CRT测量显示了中度的一致性 (ICC = 0.499).
- 10.0N和10.5N的压力显示出强大的一致性和可靠性 (ICC = 0.790).
结论:
- 对于稳定的CRT测量,建议使用4.5N-10.5N的压力范围.
- 对于CRT评估的最佳一致性和可靠性是通过10.0N-10.5N的施加力实现的.
- 这些发现支持开发压力控制CRT测量的标准化协议.
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