在台湾,分子检测新出现的猪肉循环病毒
Yu Fan Hung1, Po-Chen Liu1,2, Ching-Hung Lin1
1Graduate Institute of Veterinary Pathobiology, National Chung Hsing University, Taichung City, 402202, Taiwan.
Heliyon
|August 22, 2024
概括
猪肉环状病毒2型和3型 (PCV2,PCV3) 在台湾仍然普遍存在,PCV3可能是内在的. 该研究还报告了台湾首次检测到猪肉病毒4型 (PCV4),该病毒被归类为PCV4b.
科学领域:
- 兽医病毒学 兽医病毒学
- 猪病流行病学 猪病流行病学
- 分子诊断学 分子诊断
背景情况:
- 猪圈病毒2型 (PCV2) 是一个全球性的重大猪病原体,造成经济损失.
- 新出现的3型 (PCV3) 和4型 (PCV4) 猪病毒对猪健康构成越来越大的威胁.
- 台湾PCV3的流行病学尚不清楚,PCV4也没有被确定.
研究的目的:
- 确定台湾养猪场中PCV2的流行情况.
- 调查台湾PCV3的流行病学.
- 为了检测台湾猪中PCV4的存在.
主要方法:
- 在2020年9月至2021年12月期间,从46个临床病例收集了128个样本.
- 使用分子方法检测PCV2,PCV3和PCV4.
- 确定PCV3和PCV4菌株的全基因组测序和遗传学分析.
主要成果:
- 病例检测率为PCV2的54.3%,PCV3的43.5%和PCV4.2的2.2%.
- 在所有7个采样县和11个采样月检测到PCV3,这表明流行性.
- 第一个台湾PCV4菌株被识别并根据帽子蛋白分析将其分类为PCV4b类.
结论:
- 台湾猪中PCV2和PCV3的流行率很高.
- PCV3可能代表台湾的特有感染,已识别出明显的台湾类和日本类菌株.
- 台湾PCV4的出现得到证实,强调需要对新型猪病原体进行持续监测.
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