在估计基底细胞癌的身体脂肪百分比与体重指数
Zheng Dong1,2, Zhenyu Chen3, Qian Tan1,2
1Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, 210008, China.
Heliyon
|August 22, 2024
概括
身体脂肪百分比 (BFP) 是比身体质量指数 (BMI) 更敏感的基底细胞癌 (BCC) 风险指标. 较高的BFP与BCC风险增加有关,而BMI显示没有显著的关联.
科学领域:
- 皮肤病学 皮肤病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 身体质量指数 (BMI) 与基底细胞癌 (BCC) 风险之间的关联受到争论.
- 有限的数据存在于其他物理测量,如身体脂肪百分比 (BFP),作为BCC风险因素.
- 这是一个很棒的节目,这是一个很棒的节目.
研究的目的:
- 调查身体脂肪百分比 (BFP) 和基底细胞癌 (BCC) 风险之间的关联.
- 为了比较BFP与BMI作为BCC风险预测指标的有效性.
主要方法:
- 来自两个中国中心 (2015-2022) 的临床数据的回顾性分析.
- 包括337名年龄在50-91岁之间的患者.
- 统计分析包括单变量,分层和多重逻辑回归,以及元分析.
主要成果:
- 在研究队列或元分析 (OR:0.99,P=0.8) 中,BMI和BCC风险 (OR:0.71,P=0.3186) 之间没有发现显著的关联.
- 身体脂肪百分比 (BFP) 与BCC风险增加显著相关 (OR:2.64,P=0.0196).
- 与BMI相比,BFP显示出更强的临床证据作为风险因素.
结论:
- 身体脂肪百分比 (BFP) 是基底细胞癌 (BCC) 的一个比BMI更敏感的危险因素.
- 常规医疗保健可以从将BFP测量纳入BCC风险评估中受益.
- 减少身体脂肪可能有利于BCC辅助治疗.
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