恶性部曲失败综合征:与恶性状体综合征相比,一种瘤疾病
Yojiro Ishikawa1, Satoshi Teramura1, Kengo Ito1
1Radiology, Tohoku Medical and Pharmaceutical University, Sendai, JPN.
Cureus
|August 22, 2024
概括
恶性部曲性衰竭综合征 (MHFFS) 与恶性psoas综合征 (MPS) 不同,其特点是部曲问题而不是不移动. 早期放射治疗显示出对MHFFS症状管理的前景.
科学领域:
- 在瘤学瘤学.
- 辐射疗法 辐射疗法
- 肌肉骨瘤学 肌肉骨瘤学
背景情况:
- 恶性psoas综合征 (MPS) 涉及瘤的psoas肌肉入侵,导致疼痛的部固定.
- 一种不同的疾病,恶性部曲性衰竭综合征 (MHFFS),源于psoas肌附近的瘤,导致部曲性缺陷,但没有严重的疼痛.
研究的目的:
- 根据瘤的位置来定义恶性部曲失效综合征 (MHFFS).
- 为了比较MHFFS与古典恶性psoas综合征 (MPS) 的患病率,临床特征和结果.
- 引入并评估"石川和田村 (IT) 标志"对MHFFS的临床意义.
主要方法:
- 对291名接受息性放射治疗 (RT) 的患者进行分析,以治疗腰部,骨盆或腿部下部瘤 (2013-2023年).
- 在MHFFS和MPS之间比较流行,病理,临床表现,治疗和结果.
- 在MHFFS案件中对"IT标志"的定义和评估.
主要成果:
- 在291名患者中,MHFFS在6名 (2.1%) 患者和MPS在11名 (3.8%) 患者中被发现.
- MHFFS瘤位于胸椎/腰椎或小三角骨,呈现出部/大腿部疼痛和曲功能障碍.
- 所有MHFFS病例都表现出一种积极的IT标志;50%的患者在RT时表现出症状改善. MPS需要更强大的疼痛管理 (阿片类药物).
结论:
- MHFFS是一种独特的综合征,其特征是部曲失效,可通过IT标志识别.
- 早期的放射治疗可能有助于管理MHFFS症状.
- 虽然这两种情况的平均存活时间为13.2个月,但MHFFS似乎对RT的反应比MPS更快.
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