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Updated: Jun 15, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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造结构复杂性:密集替代β-乳酸盐的二重选择合成,具有双重功能手柄,用于增强核心修改

Agustin M Rodriguez Treviño1, Pierre Loch-Temzelides1, Sanjay Pandiri1

  • 1Department of Chemistry, Rice University Houston Texas 77030 USA kurti.laszlo@rice.edu.

Chemical science
|August 22, 2024
PubMed
概括

合成具有C-Br和N-O键的β-乳酸盐具有挑战性. 这项研究引入了一种新的NBS介导的循环化方法,以有效地产生多样化的α-bromo N-alkoxy beta-lactams.

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