根据社会生态模型,在老年慢性阻塞性肺部疾病患者中开发和验证吸入器疗法不遵守的诺姆图
You-Ran Liu1, Yan Wang2, Juan Chen3
1School of Nursing, Bengbu Medical University, Bengbu, People's Republic of China.
Patient preference and adherence
|August 22, 2024
概括
预测老年COPD患者的不坚持是可以使用nomogram. 关键因素包括信念,感知和吸烟状况,有助于个性化干预,以更好地遵守吸入器治疗.
科学领域:
- 肺部医学 肺部医学
- 老年病的医生 老年病的医生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 对于患有慢性阻塞性肺病 (COPD) 的老年患者来说,不坚持吸入器治疗是一个重大挑战.
- 识别不遵守的预测因素对于开发有效的管理策略至关重要.
- 之前的研究还没有充分解决中国这一特定人口群体的预测模型.
研究的目的:
- 为了确定中国老年COPD患者的吸入器治疗不坚持的风险预测因素.
- 构建和验证这个人群中的非坚持性名ogram预测模型.
主要方法:
- 一项涉及中国安305名老年COPD患者的横截面研究.
- 使用吸入器粘附测试评估的坚持;通过基于社会生态模型的问卷收集的预测因素.
- 统计分析包括 LASSO 和使用 R 版本 4.3.3.3. 的多变量逻辑回归.
主要成果:
- 不坚持药物的重要危险因素包括药物信仰,疾病感知,COPD评估测试得分,吸烟状况和教育水平 (P <0.05).
- 诺米图表表现出良好的区分能力 (AUC = 0.912,C指数 = 0.922) 和校准 (布里尔值 = 0.070).
- 决策曲线分析表明,当不坚持的概率超过17%时,临床效用.
结论:
- 在老年COPD患者中成功开发了一种用于预测吸入器疗法不坚持的预测性名录.
- 该名录使医疗保健专业人员能够快速评估不合规风险,并指导个性化干预.
- 这种工具可以改善老年人COPD的临床管理和患者结果.
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