在使用盖茨协议进行GFR估计时进行深度校正的侧向后侧方法:它是否与通过血采样进行黄金标准GFR估计相提并论?
1Department of Nuclear Medicine, Sadhu Vaswani Missions Medical Complex, Pune, Maharashtra, India.
World journal of nuclear medicine
|August 22, 2024
概括
盖茨协议中的深度校正用于用膜过率 (GFR) 估计,使用玛相机光学并没有提高准确性. 侧向后部方法显示偏差比马相机方法少,但两者都不匹配血采样GFR.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 核医学是一种核医学.
- 放射学 放射学是一门学科.
背景情况:
- 使用盖茨协议与相机二乙三胺五酸 (DTPA) 动态瘤学估计的淋巴细胞过率 (GFR) 经常显示与黄金标准血采样方法的差异.
- 这种不准确性归因于标准盖茨协议中对深度普遍缺乏考虑.
- 研究手动深度校正方法的目的是提高造术中GFR估计的准确性.
研究的目的:
- 评估手动深度校正,特别是使用侧向视图中的皮肤到的距离和后侧侧后 (PALP) 方法,与血采样相比,减少盖茨GFR测量的偏差.
- 为了比较两个深度校正技术的有效性:直接的马相机测量和PALP方法.
主要方法:
- 对27名成年潜在脏捐赠者进行了回顾性分析.
- 参与者在2022年1月至2023年4月期间接受了黄金标准GFR和DTPA动态造术的血采样.
- 使用SPSS版本21.0.0进行统计分析.
主要成果:
- 没有发现血采样GFR和用玛相机方法估计的GFR与或没有侧向后部深度校正之间的显著一致.
- 在与血采样GFR相比,加深校正的马相机方法显示较低的系统偏差与侧向后部方法相比.
- 两种深度校正方法都无法充分调和学和基于血的GFR测量之间的差异.
结论:
- 基于玛摄像头的盖茨协议GFR估计中的横向后方深度校正方法对于印度西部成年人群具有保留功能是不可靠的.
- 需要进一步的研究来完善动态学中的GFR估计技术,以实现与基于等离子体的黄金标准更好的相关性.
更多相关视频
11:47Using 2-Photon Microscopy to Quantify the Effects of Chronic Unilateral Ureteral Obstruction on Glomerular Processes
Published on: March 4, 2022
2.2K
11:13Quantifying Glomerular Permeability of Fluorescent Macromolecules Using 2-Photon Microscopy in Munich Wistar Rats
Published on: April 17, 2013
10.4K
相关概念视频
Determination of Renal Drug Clearance: Graphical and Midpoint Methods
90
Renal clearance, a crucial parameter in pharmacokinetics, can be determined using two different methods: the graphical method and the midpoint method. These methods provide insights into the rate of drug excretion by the kidneys and aid in assessing renal function.
The graphical method involves plotting the rate of drug excretion in urine against the plasma drug concentration. By analyzing the graph, the clearance can be calculated and obtained. Drugs rapidly excreted by the kidneys exhibit a...
The graphical method involves plotting the rate of drug excretion in urine against the plasma drug concentration. By analyzing the graph, the clearance can be calculated and obtained. Drugs rapidly excreted by the kidneys exhibit a...
90
Renal Clearance
802
The glomerular filtration rate (GFR) is a critical marker of kidney function, reflecting the efficiency of filtration by the glomeruli. Renal clearance of specific substances, such as inulin or creatinine, is commonly used to measure GFR.
Renal clearance refers to the volume of plasma cleared of a specific substance, such as creatinine, per unit of time. To measure clearance, urine samples are collected over a 24-hour period during each bladder voiding, followed by a single blood sample at the...
Renal clearance refers to the volume of plasma cleared of a specific substance, such as creatinine, per unit of time. To measure clearance, urine samples are collected over a 24-hour period during each bladder voiding, followed by a single blood sample at the...
802
