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通过逆行神经追踪来理解向侧向后部的甲状腺核及其子区域的皮层下投影

Hisashi Nakamura¹, Keisuke Ohta^1,2

¹Division of Microscopic and Developmental Anatomy, Department of Anatomy, Kurume University School of Medicine, Kurume, Japan.

Frontiers in neuroanatomy

|August 22, 2024

概括

这项研究将皮层下投影映射到老鼠的侧向后部体核 (LP). 侧向后部 (LPl) 和侧向中部 (LPrm) 部分接收不同的输入,这表明LPl是视觉特异性的,而LPrm集成了多种感官模式.

科学领域:

神经科学是一个神经科学.
泰拉姆细胞的电路.
感官处理感官处理

背景情况:

鼠的侧侧后核 (LP) 有不同的子区域,包括LPrm和LPl,参与视觉处理.
对LPrm和LPl的特定皮质下连接尚不清楚.

研究的目的:

在大鼠中研究和区分LPrm和LPl的皮下投射.
根据它们的连接模式,阐明LPrm和LPl的功能角色.

主要方法:

使用一个逆行神经标记器,Fluorogold (FG),注射到LPrm和LPl.
采用免疫组织化学,可视化脑部各个区域的逆行标记神经元.

主要成果:

从视网膜,双大脑 (Rt,ZI,LGv,IGL,下丘脑),中脑 (PAG,上结核),小脑和三角核中,LPrm接收了投影.
LPl从视觉区域 (视网膜,LGv,IGL,OPT,APT) 和Rt接收了投影,小脑和中枢的输入较少.
LPrm显示了ZI,网状形成和PAG的较高相对输入,而LPl从APT,OPT和Rt获得了更多的输入.

结论:

LPrm似乎可以整合视觉,感官和运动信息,表明更广泛的功能角色.
LPl主要参与视觉特定处理.
这些发现增强了对乳头皮下皮质电路及其对感官感知和运动整合障碍的影响的理解.

关键词:

黄金化物黄金化物侧面的后部核.周边水道灰色周边水道灰色预测面积的预测面积是什么普尔维纳尔 (Pulvinar) 是一个火车站.上级结体 (上级结体)

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