在老年人中,峰值呼气流与运动认知风险综合征的关联
Hui Xu1, Xiangwen Gong2, Kaiwang Cui2
1Big Data Center, Beijing Children's Hospital, National Center for Children's Health, Capital Medical University, Beijing, China.
更高的峰值呼气流 (PEF) 与运动认知风险综合征 (MCR) 的流行率和风险降低有关. 增加的PEF还延迟了MCR的出现,这表明它对肺功能起着保护作用.
科学领域:
- 老年学是指老年学的学科.
- 肺部病理学 肺部病理学
- 神经学 神经学
背景情况:
- 肺功能和运动认知风险综合征 (MCR) 之间的关系仍然不太清楚.
- 调查峰值呼气流 (PEF) 和MCR之间的关联对于了解神经退行性疾病风险因素至关重要.
研究的目的:
- 探索峰值呼气流 (PEF) 与运动认知风险综合征 (MCR) 的患病率和发病率之间的联系.
- 确定更高的PEF是否与较低的MCR风险或延迟发病相关.
主要方法:
- 通过查尔斯队列的数据进行了横截面和纵向分析.
- 使用肺峰值流量计测量了峰值呼气流量 (PEF).
- 运动性认知风险综合征 (MCR) 定义为认知投诉,慢步行速度,正常移动性和没有痴呆症. 使用了逻辑,考克斯和拉普拉斯回归模型.
主要成果:
- 在横截面分析中,更高的连续PEF与较低的MCR患病率显著相关.
- 在纵向分析中,更高的PEF与剂量依赖性相关,与发生MCR的风险降低有关.
- 与最低的三分之一相比,最高的PEF三分之一与显著较低的风险和延迟的MCR发作有关.
结论:
- 增加的峰值呼气流 (PEF) 与运动认知风险综合征 (MCR) 的流行率和发病率降低有关.
- 更高的PEF可能会对MCR的发展和进展产生保护作用,可能会延迟其发作.
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