[下骨的状况在压缩-分心骨质合成后的远期再生]
A G Nadtochiy1, I A Ovchinnikov1, E V Alborova1
1Central Research Institute of Dentistry and Maxillofacial Surgery, Moscow, Russia.
概括
压缩分散骨质合成 (CDO) 能够有效地再生下微骨的骨,产生与完整骨相比的结果. 这种技术可以作为重建性手术的可行治疗方法.
科学领域:
- 口腔和牙面部外科手术
- 再生医学是一种再生医学.
- 生物材料科学 生物材料科学
背景情况:
- mandibular micrognathia 在重建性手术中提出了一些挑战.
- 压缩分散骨质合成 (CDO) 是一种用于解决骨差异的技术.
- 了解长期骨再生特征对于治疗规划至关重要.
研究的目的:
- 为了评估骨再生后的质量和数量特征CDO在患者下微.
- 为了比较先天性和获得性微骨之间的骨再生特征.
- 评估再生的长期稳定性和骨质整合.
主要方法:
- 对30名用CDO治疗的下微的患者的分析.
- 分类为先天性 (n=16) 和获得的 (n=14) 微型形群.
- 利用3D建模,形态分析和多切片计算机断层扫描 (MSCT) 与霍恩斯菲尔德尺度用于骨密度评估.
主要成果:
- 骨再生显示了尺寸变化:长度下降,而厚度和高度在两组都增加.
- 在CDO后,先天性微症组表现出下支和身体长度的较大增加.
- 再生的骨密度与完好无损的骨密度紧密相匹配,骨密度略有降低.
结论:
- 在CDO之后的长期骨再生显示了与完整骨相比的质量和数量特征.
- CDO是一种可行的治疗选择,用于下微,作为一个预备和独立的重建程序.
- 这些发现支持使用CDO来实现下骨的稳定和功能性骨重建.
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