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孕妇X受体通过降低质素表达的调节来抑制肝星细胞的转基因分化

Takumi Sato1, Ryota Shizu1, Ryonosuke Baba1

  • 1Laboratory of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526 Japan.

The Biochemical journal
|August 22, 2024
PubMed
概括

肝星细胞中的孕妇X受体 (PXR) 激活通过抑制POSTN,细胞转基因的关键因素,抑制肝癌的上皮细胞-介质细胞过渡 (EMT).

关键词:
肝脏的恒星细胞.肝癌 肝癌 是一种肝癌.核受体是一种核受体.怀孕前的X受体受体

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