脂肪状况对唾液中的Streptococcus mutans和Streptococcus sobrinus的影响
Qianyi Deng1,2,3, Hai Ming Wong1, Simin Peng1
1Paediatric Dentistry and Orthodontics, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.
Oral diseases
|August 22, 2024
概括
青少年的肥胖,无论是一般的还是中央的,都与唾液中引起空洞的细菌Streptococcus mutans的水平增加有关. 对于Streptococcus sobrinus,没有观察到这种关联.
科学领域:
- 口腔微生物学 口腔微生物学
- 青少年健康 青少年健康
- 肥胖研究的研究.
背景情况:
- 牙腐烂的细菌,Streptococcus mutans和Streptococcus sobrinus,是导致牙腐烂的关键因素.
- 肥胖是青少年中日益严重的公共卫生问题.
- 肥胖,唾液参数和特定的菌细菌之间的关系需要进一步研究.
研究的目的:
- 检查肥胖状况,唾液物理化学性质和炎症标志物对香港青少年唾液中Streptococcus mutans和Streptococcus sobrinus的丰度的影响.
- 为了确定超重/肥胖是否与这些细菌的较高水平相关.
主要方法:
- 一项涉及180名香港青少年 (年龄在12-15岁) 的横截面研究.
- 收集人体测量数据,口腔健康状况和唾液样本.
- 分析唾液的物理化学参数,蛋白质生物标志物和细菌负载 (Streptococcus mutans,Streptococcus sobrinus,总细菌).
主要成果:
- 与瘦肉对照组相比,一般或中心肥胖的青少年表现出明显更高的唾液Streptococcus mutans丰富度和总细菌数量.
- 在肥胖青少年中观察到更低的刺激唾液流速和降低的分泌脂酶A2IIA组水平.
- 总体超重/肥胖和中心肥胖独立地与增加唾液性Streptococcus mutans的更高可能性有关.
结论:
- 一般和中心肥胖与青少年唾液中Streptococcus mutans水平的增加有显著的关联.
- 肥胖状况与Streptococcus sobrinus的唾液丰度没有显著的关联.
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