用于药物代谢物的先进输送的植物体细胞纳米构造:深入审查
Vishal Pandey1, Sunny Rathee1, Debasis Sen1
1Department of Pharmaceutical Sciences, Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, Madhya Pradesh, 470003, India.
Current drug targets
|August 22, 2024
概括
植物体技术提高了植物衍生植物化学物质的生物可用性和稳定性,增强了它们在各种生物系统中的治疗潜力. 本综述强调了天然产品制药的植物体配方和二次代谢物的进展.
科学领域:
- 自然产品化学 自然产品化学
- 药理学 药理学是指药理学的学科.
- 生物技术是生物技术.
背景情况:
- 植物化学物质提供治疗效益,但其生物可用性和稳定性较差.
- 植物体技术封装了生物活性植物化合物,以提高吸收和疗效.
研究的目的:
- 审查植物体技术的进步,以提高植物化学物质的输送.
- 探索二次代谢产物及其植物体配方的治疗潜力.
主要方法:
- 关于植物体技术和二次代谢产物的最新文献的综述.
- 对专利的植物体配方及其对稳定性和生物可用性的影响进行分析.
- 关键二次代谢物的分类和生物活性评估.
主要成果:
- 植物体显示出广泛的治疗效益,包括心血管,神经,胃肠道,肝保护性,脏,免疫和皮肤学影响.
- 植物体技术的创新提高了稳定性和生物可用性,尽管商业化面临挑战.
- 二次代谢物,如类和类,具有显著的抗微生物,抗氧化和抗炎活性.
结论:
- 植物体技术显著提高了植物化学品和二次代谢物的治疗效用.
- 需要进一步开发,以克服商业化障碍,以获得广泛的临床应用.
- 本综述提供了植物体和二次代谢物研究的整体观点,以推进基于天然产品的医学.
更多相关视频
09:34Uptake of New Lipid-coated Nanoparticles Containing Falcarindiol by Human Mesenchymal Stem Cells
Published on: February 9, 2019
8.9K
06:57Rapid, Scalable Assembly and Loading of Bioactive Proteins and Immunostimulants into Diverse Synthetic Nanocarriers Via Flash Nanoprecipitation
Published on: August 11, 2018
7.9K
相关概念视频
Mechanisms of Drug Absorption: Paracellular, Transcellular, and Vesicular Transport
479
Drugs need to permeate cell membranes to reach their target sites after administration. Orally administered drugs must transcend intestinal epithelial membrane barriers to infiltrate the systemic circulation. Drugs with a molecular weight of less than 500 Daltons diffuse through gaps between neighboring cells, called paracellular pathways.
However, most drugs use the transcellular route, traversing directly through the cell membranes via two mechanisms: passive and active transport. Passive...
However, most drugs use the transcellular route, traversing directly through the cell membranes via two mechanisms: passive and active transport. Passive...
479
Drug Delivery: Overview
279
The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
279
