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Updated: Jun 15, 2025

Basement Membrane Matrix Encapsulated Cell Aggregation for Investigating Murine Spleen Tissue Formation
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骨髓状细胞的跨组织组织在硬化皮质症和相关纤维性疾病中

Ian D Odell1,2

  • 1Department of Dermatology.

Current opinion in rheumatology
|August 22, 2024
PubMed
概括

单细胞RNA测序揭示了一个新的树突细胞子集 (DC3),富含皮肤和肝脏等纤维组织. 在肺,心脏和纤维化中发现了SPP1巨细胞,突出显示了器官特异性髓状细胞在疾病中的作用.

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Extracellular Matrix

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Introduction to Connective Tissues

Connective tissues are one of the four main tissue types in humans that are extensively present in the body. They are characterized by cells embedded in an extracellular matrix (ECM) composed of a ground substance and three main types of protein fibers— collagen, elastic, and reticular fibers. The ground substance of connective tissues can range from a watery and jelly-like consistency to mineralized and hard. The wide variety of cells in the connective tissues include fibroblasts,...
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