"安全网":评估康复教练和护理人员干预在阿片类药物过量后的纳洛复苏后的评估
Daniel Joseph1,2, Carolyn Brokowski1,3, Gail D'Onofrio1,4,5
1Department of Emergency Medicine, Yale School of Medicine, New Haven, CT, USA.
Substance use & addiction journal
|August 22, 2024
概括
安全网计划,使用恢复教练和护理人员过量后,没有显著减少后续过量或MOUD参与. 然而,许多参与者确实参与了针对阿片类药物使用障碍 (MOUD) 的门诊药物治疗.
科学领域:
- 成 药物 药物 药物 药物
- 紧急医疗 紧急医疗
- 公共卫生 公共卫生
背景情况:
- 紧急部门 (ED) 发起的布普伦诺芬是有效的,但面临着患者的不情愿.
- 过量服用阿片类药物仍然是一个关键的公共卫生问题,需要创新的干预措施.
- 治疗阿片类药物使用障碍 (MOUD) 的药物对恢复和减少过量死亡至关重要.
研究的目的:
- 评估SafetyNet计划在减少ED后阿片类药物过量使用后的有效性.
- 评估该计划对参与MOUD的患者的影响.
- 为了确定该计划在减少过量幸存者的非法药物使用中的有效性.
主要方法:
- 对过量服用和拒绝ED布诺啡的人进行前性非随机研究.
- 干预涉及恢复教练和护理人员 (RCP) 团队,提供简短的谈判访谈 (BNI),同行恢复指导和健康教育.
- 在30日和180天后进行后续评估,以测量过量事件,MOUD参与和尿液毒理学.
主要成果:
- 在81名注册患者中,有45人 (56%) 获得了随访数据;20人 (25%) 经历了随后的过量服用.
- 55名参与者 (68%) 参与了某种形式的门诊MOUD.
- 在随访和非随访组之间,在随后的过量剂量率,MOUD参与或尿液毒理学方面没有发现统计学上显著的差异.
结论:
- 与对照组相比,安全网干预没有显示过量事件或MOUD参与的显著减少.
- 参与者的高比例 (68%) 启动了门诊MOUD,这是一种与减少过量死亡率相关的治疗.
- 研究的局限性包括COVID-19大流行和未满足的样本大小;对SafetyNet潜在益处的进一步研究是有必要的.
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