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Updated: Jun 15, 2025

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宏细胞殖民地刺激因子受体/CD115+非经典单细胞在全身性红斑狼中扩大,并与狼性炎相关

M Zeisbrich1, R Rzepka1, S Finzel1

  • 1Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Freiburg im Breisgau, Germany.

Scandinavian journal of rheumatology
|August 22, 2024
PubMed
概括

在全身性红斑狼 (SLE) 中,表达M-CSF受体CD115的扩大非经典单细胞与狼性炎有关. 这种单细胞子集也共同表达slan,提供潜在的诊断见解.

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Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are essential for protecting the body against bacterial, viral, or fungal infections. They migrate from the bone marrow into the circulating blood to reach specific tissue sites where they differentiate and help in immune surveillance. However, they survive only for a few days and must be continuously made available to the organism to maintain a robust...
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