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Updated: May 7, 2026

Interactome-Seq: A Protocol for Domainome Library Construction, Validation and Selection by Phage Display and Next Generation Sequencing
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通过使用DNA编码库发现活细胞上的膜蛋白

Yiran Huang1, Rui Hou1,2, Fong Sang Lam1

  • 1Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR 999077, China.

Journal of the American Chemical Society
|August 22, 2024
PubMed
概括

研究人员开发了一种新方法, 通过活细胞上的DNA编码库 (DEL) 来发现激活膜蛋白的药物分子. 这种方法成功地发现了EGFR,TPOR和INSR等关键受体的新兴激素.

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