大脑与心脏的相互作用在四种常见的神经疾病中划分心脏功能障碍:系统性审查和元分析
Amal Rezk1, Winnie Liu2, Kristof Nijs3
1Department of Anesthesia and Pain Medicine, Toronto Western Hospital, University Health Network, Toronto.
Journal of neurosurgical anesthesiology
|August 22, 2024
概括
心血管疾病 (CD) 与神经系统疾病有关,总发病率为10%. 头部损伤显示CD发病率最高 (28%),而显著增加CD风险 (2.25概率比).
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 公共卫生 公共卫生
背景情况:
- 神经和心血管疾病是全球疾病和死亡的主要原因.
- 人们越来越认识到心血管疾病 (CD) 和神经系统疾病之间的相互关系.
- 了解CD对神经疾病的影响对于公共卫生战略至关重要.
研究的目的:
- 系统地审查和元分析CD在四种常见的神经系统疾病的综合发病率和相关性:偏头痛,阿尔茨海默氏症/痴呆症,和头部损伤.
- 量化患有这些神经疾病的患者患有CD的风险.
- 确定哪些神经系统疾病与CD有最强烈的关联.
主要方法:
- 65项研究的系统审查和元分析.
- 包括超过450万个患者记录.
- 基于残疾调整寿命年的分析,以确定聚合发病率和关联.
主要成果:
- 在四种神经系统疾病中,CD的总体综合发病率为10%.
- 头部损伤显示CD发病率最高 (28%),其次是偏头痛 (9.6%).
- 神经系统疾病增加了CD发展的几率两倍;显示最大的增加的几率 (OR: 2.25).
结论:
- 神经系统疾病显著与患心血管疾病的风险增加有关.
- 头部受伤和是关键的神经疾病,具有伴随性CD的风险.
- 需要进一步的大规模前性研究来阐明长期结果.
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