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Updated: Jun 15, 2025

All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System
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All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System

Published on: December 20, 2021

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网林-1和UNC5B与整蛋白合作,以调解YAP驱动的细胞静止

Joel D Pearson1,2,3,4, Katherine Huang1, Louis G Dela Pena4

  • 1Lunenfeld Tanenbaum Research Institute, Mt Sinai Hospital, Sinai Health System, Toronto, Canada.

Cancer research communications
|August 22, 2024
PubMed
概括

YAP/TAZ蛋白质可以通过诱导Netrin-1/UNC5B和integrin-αV/β5来抑制YAPoff癌症中的瘤,从而揭示出一种新的抗癌途径. 这一发现挑战了网红蛋白在癌症进展中的已知作用.

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